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250mg Citruvia™ (Citrus Sinensis L. Bioflavonoid)

Hemodas™ key active ingredient Citruvia™ is a bioflavonoid isolated from citrus fruits mainly sweet orange (Citrus sinensis (L.) Osbeck).

Citruvia™ Citrus Sinensis L. Bioflavonoid Complex is chemically a flavone derivative, which is defined as the 7-rhamnoglucoside of 5,7,3’-trihydroxy-4’-methoxyflavone.

What is Hemodas™?

  • Hemodas™ is clinically studied to support vascular health
  • Hemodas™ is simple, fast, effective by supporting anal veins and blood vessels
  • Hemodas™ helps alleviate occasional anal discomfort
  • Hemodas™ is a discreet oral solution, an easy to swallow tablet.
  • Hemodas™ is purified from naturally occurring citrus bioflavonoids.

Hemodas™ active ingredient has been used for over 20 years in Europe to support anal health. In fact, over 600 million tablets are sold in France every year and over 3 billion tablets sold annually worldwide.

Thirty total published human clinical studies.

Two Double Blind indicate support for anal health studies. Efficacy and dosage regimen of diosmin  validated in two double blind studies:

  1. Against placebo, in 94 patients. Chauvenet and Libeskind, 1994
  2. Against a reference product, in 127 patients.  Debien and Denis, 1996.

How does Hemodas™ work?

Hemodas™ works by supporting the strength of veins and blood vessels, and prompting normal inflammatory response.  As an antioxidant Hemodas™ fights free-radical damage and stimulates lymphatic flow.  Hemodas™ promotes the well-being of veins and blood vessels.   Hemoda™s helps maintain healthy blood flow through your capillaries—the most fragile of your blood vessels.   Hemodas™ also helps to maintains the tone and elasticity of your veins—the key to sustained vascular health which helps alleviate occasional anal discomforts.

  • Hemodas™ promotes venous tone.  Phlebotoni Mechanism, Hemodas™ reinforces venous tone and reduces vein distension while supporting venous return-blood flow.
  • Hemodas™ has a positive effect regarding the inflammatory process and edema.  Hemodas™ is also a potent inhibitor of inflammation mediators (lipoxygenase, PGE2, TxA2).
  • Hemodas™ Inhibits leukocites activation, migration and adhesion.
  • Hemodas™ supports capillary health and permeability, capillary resistance is strengthened, capillary bed microcirculation is increased.
  • Hemodas™ supports the endothelium at the microcirculation & valves level
  • Hemodas™ acts as an Antioxidant, supporting vein cell wall membrane from acute stress and aging.

 

Hemodas™ works by promoting the tone & strength of veins and blood vessels.
 Hemodas™ works by increasing circulation and normal inflammatory response.

Hemodas™ works by acting as an antioxidant and reducing free radical damage.

Is Hemodas™ right for me?

Hemodas™ is for anyone looking to improve anal health, tone and comfort.  Once orally ingested, Hemodas™ works from the inside out supporting anal blood vessels and vein.

Our active ingredient has been used for decades in Europe.

How often should I take Hemodas™?

  • 1 tablets, 3Xs per day for 4-5 days, followed by 1 tablet for 3 more days.  Consume with water during meals, 1-2 tablets with lunch, 1-2 tablets with dinner.
  • For reducing frequency of flare-ups and overall anal tissue support.
  • 1 tablet daily thereafter.

How quickly does Hemodas™ work?

For best results consume the product for a minimum of 8 days.  In clinical studies Hemodas™ has been shown to support venous and delicate capillary tissues in the anal region.

Do I need a prescription?

No. In the US this product is a dietary supplement and may be marketed directly to consumer.

Side Effects

As a water soluble citrus bioflavonoid Hemodas™ is well tolerated. Occasional side effects are rare but can include stomach upset, diarrhea and nausea.  Some people may experience slight headaches.  No serious adverse events have been reported, millions of tablets are consumed annually.

Safety

about-graph1Hemodas™ has an outstanding safety record.

The active ingredient in Hemodas™ has been prescribed millions of times in Europe for the last two decades.  Hemodas™ is a unique formulation of water soluble citrus bioflavonoids, the main mechanism of action is antioxidant activity and free radical elimination. Hemodas™ is well tolerated and has safely used over 20 years.

 

HEMODAS™ Historical Timeline

1925 Citrus Sinensis L. Bioflavonoid Complex was first isolated from Scrophularia nodosa plant.
1936 Dr Albert Szent-Gÿorgi (Hungarian researcher) found that Citrus peel flavonoids were effective in supporting anal health.
1969 Citrus Sinensis L. Bioflavonoid Complex was first introduced in Europe.
1971 Citrus Sinensis L. Bioflavonoid Complex was first launched in France as a vegetal extract by Les Laboratoires Servier to support venous health in the legs and anal regions.
1986 Citrus Sinensis L. Bioflavonoid Complex was launched as a purified and micronized flavonoid fraction (PMFF) containing 90% Citrus Sinensis L. Bioflavonoid Complex and 10% of hesperidin with an average particle size ≤ 2 µm (in venous health support).
1992 Thanapongsathorn1 demonstrated support of congestion caused by  anal discomfort
1995 Cospite and Godeberge published main studies demonstrating the efficacy and acceptability and proving that PMFF diosmin and hesperidia supported anal health.
1997 Buckshee et al proved the safety, efficacy and acceptability of PMFF Citrus Sinensis L. Bioflavonoid Complex 90% and hesperidin 10% supports anal health during pregnancy.
1999 First launch of 600mg Citrus Sinensis L. Bioflavonoid Complex tablets in France.
2000 Jantet confirmed the safety and efficacy of PMFF treatment through a European study in more than 10’000 patient suffering from CVI. The study showed significant improvement in the symptoms and signs of CVI and quality of life of patient.
2002 A monograph on Citrus Sinensis L. Bioflavonoid Complex has been included in the 4th Edition of the European Pharmacopoeia.
2004 Maruszynski7 compared the clinical effectiveness of  Hemodas™ (600mg Citruvia™ Citrus Sinensis L. Bioflavonoid Complex) tablets with a drug containing 90% PMFF of Citrus Sinensis L. Bioflavonoid Complex and 10% hesperidin in women for venous health.
2006 New Dietary Ingredient (NDI) notification for 720 mg tablets containing Citruvia™ (600mg Citrus Sinensis L. Bioflavonoid Complex) was submitted to FDA.